This image shows Christina Wege

Christina Wege

Prof. Dr. (apl.)

Head of Research Unit Molecular & Synthetic Plant Virology

Contact

+49 711 685 65073

Pfaffenwaldring 57
70569 Stuttgart
Germany
Room: 9-558

Office Hours

Thu 10:30-11:30

 

Subject

Molecular Plant Virology:
Molecular biology of viral plant diseases, interactions of plants and viruses in single an mixed infections - focus: geminiviruses

Synthetic Plant Virology - Biomaterials and Bionanotechnology:
Plant viral derivatives for intelligent nanostructured hybrid materials  ("Smart Materials") and building-blocks in analytical, technical & therapeutic applications - focus: tobacco mosaic viruses

→ Projekthaus NanoBioMater: Coordinator

 
  • Wendlandt, T., Britz, B., Kleinow, T., Hipp, K., Eber, F.J., Wege, C. (2024). Getting hold of the tobamovirus particle - why and how? Purification routes over time and a new customizable approach. Viruses, Special Issue "Tobamoviruses: Molecular Aspects and Resistance Regulation—a Special Issue Commemorating 125 Years of Research on Tobamoviruses", 16, 884. https://doi.org/10.3390/v16060884
  • Grübel, J., Wendlandt, T., Urban, D., Jauch, C.O., Wege, C., Tovar, G.E.M., Southan, A. (2023). Soft sub-structured multi-material biosensor hydrogels with enzymes retained by plant viral scaffolds. Macromolecular Bioscience, e2300311. https://www.ncbi.nlm.nih.gov/pubmed/37922890
  • Wendlandt, T., Koch, C., Britz, B., Liedek, A., Schmidt, N., Werner, S., Gleba, Y., Vahidpour, F., Welden, M., Poghossian, A., Schöning, M.J., Eber, F.J., Jeske, H., Wege, C. (2023). Facile purification and use of tobamoviral nanocarriers for antibody-mediated display of a two-enzyme system. Viruses 15, 1951. https://www.ncbi.nlm.nih.gov/pubmed/37766357
  • Welden, M., Poghossian, A., Vahidpour, F., Wendlandt, T., Keusgen, M., Christina, W., Schöning, M.J. (2023). Capacitive field-effect biosensor modified with a stacked bilayer of weak polyelectrolyte and plant virus particles as enzyme nanocarriers. Bioelectrochemistry 151, 108397. https://doi.org/10.1016/j.bioelechem.2023.108397
  • Noris, E., Pegoraro, M., Palzhoff, S., Urrejola, C., Wochner, N., Kober, S., Ruoff, K., Matić, S., Schnepf, V., Weisshaar, N., Wege, C. (2023). Differential effects of RNA-Dependent RNA Polymerase 6 (RDR6) silencing on New and Old World begomoviruses in Nicotiana benthamiana. Viruses 15, 919. https://doi.org/10.3390/v15040919
  • Geiger, F., Wendlandt, T., Berking, T., Spatz, J.P., Wege, C. (2023). Convenient site-selective protein coupling from bacterial raw lysates to coenzyme A-modified tobacco mosaic virus (TMV) by Bacillus subtilis Sfp phosphopantetheinyl transferase. Virology 578, 61-70. https://doi.org/10.1016/j.virol.2022.11.013
  • Paiva, T. O., Schneider, A., Bataille, L., Chovin, A., Anne, A., Michon, T., Wege, C. & Demaille, C. (2022). Enzymatic activity of individual bioelectrocatalytic viral nanoparticles: dependence of catalysis on the viral scaffold and its length. Nanoscale 14, 875-889. https://doi.org/10.1039/D1NR07445H
  • Welden, M., Poghossian, A., Vahidpour, F., Wendlandt, T., Keusgen, M., Wege, C. & Schöning, M. J. (2022a). Towards Multi-Analyte Detection with Field-Effect Capacitors Modified with Tobacco Mosaic Virus Bioparticles as Enzyme Nanocarriers. Biosensors 12, 43. https://doi.org/10.3390/bios12010043
  • Welden, M., Severins, R., Poghossian, A., Wege, C., Bongaerts, J., Siegert, P., Keusgen, M. & Schoning, M. J. (2022b). Detection of acetoin and diacetyl by a tobacco mosaic virus-assisted field-effect biosensor. Chemosensors 10, 218. https://doi.org/10.3390/chemosensors10060218
  • Berking, T., Lorenz, S.G., Ulrich, A.B., Greiner, J., Kervio, E., Bremer, J., Wege, C., Kleinow, T., Richert, C. (2021). The effect of pooling on the detection of the nucleocapsid protein of SARS-CoV-2 with rapid antigen tests. Diagnostics, 11, 1290. https://doi.org/10.3390/diagnostics11071290
  • Jablonski, M., Poghossian, A., Keusgen, M., Wege, C., Schöning, M.J. (2021). Detection of plant virus particles with a capacitive field-effect sensor. Analytical and Bioanalytical Chemistry, 1-10. https://doi.org/10.1007/s00216-021-03448-8
  • Jablonski, M., Poghossian, A., Severins, R., Keusgen, M., Wege, C., Schöning, M.J. (2021). Capacitive field-effect biosensor studying adsorption of tobacco mosaic virus particles. Micromachines, 12, 57. https://doi.org/10.3390/mi12010057
  • Welden, R., Jablonski, M., Wege, C., Keusgen, M., Wagner, P.H., Wagner, T., Schöning, M.J. (2021). Light-addressable actuator-sensor platform for monitoring and manipulation of pH gradients in microfluidics: a case study with the enzyme penicillinase. Biosensors, 11, 171. https://doi.org/10.3390/bios11060171
  • Poghossian, A., Jablonski, M., Molinnus, D., Wege, C., Schöning, M.J. (2020). Field-effect sensors for virus detection: from Ebola to SARS-CoV-2 and plant viral enhancers. Frontiers in Plant Science, 11, 598103. https://doi.org/10.3389/fpls.2020.598103
  • Kleinow, T., Happle, A., Kober, S., Linzmeier, L., Rehm, T.M., Fritze, J., Buchholz, P.C.F., Kepp, G., Jeske, H., and Wege, C. (2020) Phosphorylations of the Abutilon mosaic virus movement protein affect its self-interaction, symptom development, viral DNA accumulation and host range. Front. Plant Sci., 11, 1155. https://doi.org/10.3389/fpls.2020.01155
  • Wege, C., Koch, C. (2020). From stars to stripes: RNA-directed shaping of plant viral protein templates - structural synthetic virology for smart biohybrid nanostructures. Wiley Interdiscip. Rev.: Nanomed. Nanobiotechnol., 12, e1591.  https://doi.org/10.1002/wnan.1591
  • Eiben, S., Koch, C., Altintoprak, K., Southan, A., Tovar, G., Laschat, S., Weiss, I., Wege, C. (2019). Plant virus-based materials for biomedical applications: trends and prospects. Adv. Drug Delivery Rev.,  145, 96-118. https://doi.org/10.1016/j.addr.2018.08.011
  • Atanasova, P., Atanasov, V., Wittum, L., Southan, A., Choi, E., Wege, C., Kerres, J., Eiben, S., Bill, J. (2019). Hydrophobization of tobacco mosaic virus to control the mineralization of organic templates. Nanomaterials, 9 , 800.  https://doi.org/10.3390/nano9050800
  • Altintoprak, K., Farajollahi, F., Seidenstücker, A., Ullrich, T., Wenz, N.L., Krolla, P., Plettl, A., Ziemann, P., Marti, O., Walther, P., Exner, D., Schwaiger, R., Gliemann, H., Wege, C. (2019). Improved manufacture of hybrid membranes with bio-nanopore adapters capable of self-luting. Bioinspired, Biomimetic Nanobiomater., 8, 47-71. https://doi.org/10.1680/jbibn.18.00008
  • Mickoleit, F., Altintoprak, K., Wenz, N.L., Richter, R., Wege, C., Schueler, D. (2018). Precise assembly of genetically functionalized magnetosomes and tobacco mosaic virus particles generates a magnetic biocomposite. ACS Applied Materials & Interfaces, 10, 37898-37910.  https://doi.org/10.1021/acsami.8b16355
  • Wenz, N., Piasecka, S., Kalinowski, M., Schneider, A., Richert, C., Wege, C. (2018). Building expanded structures from tetrahedral DNA branching elements, RNA and TMV protein. Nanoscale, 10, 6496–6510. https://doi.org/10.1039/C7NR07743B
  • Wege, C., Lomonossoff, G.P. [Eds.] (2018). Virus-Derived Nanoparticles for Advanced Technologies. Humana Press, Springer Science+Business Media LLC, part of Springer Nature, Heidelberg, London, New York. https://doi.org/10.1007/978-1-4939-7808-3
  • Geiger, F., Wege, C. (2018). Dual functionalization of rod-shaped viruses on single coat protein subunits, in: Wege, C., Lomonossoff, G.P. (Eds.), Virus-Derived Nanoparticles for Advanced Technologies. Humana Press, Springer Science+Business Media, Heidelberg, London, New York, pp. 405-424. https://doi.org/10.1007/978-1-4939-7808-3_27
  • Wege, C., Eber, F. (2018). Bottom-up assembly of TMV-based nucleoprotein architectures on solid supports in: Wege, C., Lomonossoff, G.P. (Eds.), Virus-Derived Nanoparticles for Advanced Technologies. Humana Press, Springer Science+Business Media, Heidelberg, London, New York, pp. 169-186. https://doi.org/10.1007/978-1-4939-7808-3_11
  • Poghossian, A., Jablonski, M., Koch, C., Bronder, T.S., Rolka, D., Wege, C., Schöning, M.J. (2018). Field-effect biosensor using virus particles as scaffolds for enzyme immobilization. Biosensors and Bioelectronics, 110, 168–174.
  • Southan, A., Lang, T., Schweikert, M., Tovar, G.E.M., Wege, C., Eiben, S. (2018). Covalent incorporation of tobacco mosaic virus increases the stiffness of poly(ethylene glycol) diacrylate hydrogels. RSC Advances,  8, 4686-4694. https://doi.org/10.1039/C7RA10364F   
  • Koch, C., Poghossian, A., Schoening, M.J., Wege, C. (2018a). Penicillin detection by tobacco mosaic virus-assisted colorimetric biosensors. Nanotheranostics, 2, 184-196. https://doi.org/10.1016/j.bios.2018.03.036
  • Wege, C., Lomonossoff, G.P. (2018a). “Chapter 42” - an Afterword: Making VLPs in plants – the answer to life, the universe and everything? Facts, trends, prospects., in: Wege, C., Lomonossoff, G.P. (Eds.), Virus-Derived Nanoparticles for Advanced Technologies. Humana Press, Springer Science+Business Media, Heidelberg, London, New York, pp. 653-671. https://doi.org/10.1007/978-1-4939-7808-3 - see: backmatter
  • Poghossian, A., Jablonski, M., Koch, C., Bronder, T. S., Rolka, D., Wege, C., Schoening, M. J. (2018). Field-effect biosensor using virus particles as scaffolds for enzyme immobilization. Biosensors and Bioelectronics, 110, 168–174. https://doi.org/10.1016/j.bios.2018.03.036
  • Koch, C., Poghossian, A., Wege, C., Schoening, M.J. (2018b). TMV-based adapter templates for enhanced enzyme loading in biosensor applications in: Wege, C., Lomonossoff, G.P. (Eds.), Virus-Derived Nanoparticles for Advanced Technologies. Humana Press, Springer Science+Business Media, Heidelberg, London, New York, pp. 553-568. https://doi.org/10.1007/978-1-4939-7808-3_35
  • Dickmeis, C., Altintoprak, K., van Rijn, P., Wege, C., Commandeur, U. (2018). Bioinspired silica mineralization on viral templates, in: Wege, C., Lomonossoff, G.P. (Eds.), Virus-Derived Nanoparticles for Advanced Technologies. Humana Press, Springer Science+Business Media, Heidelberg, London, New York, pp. 337-362. https://doi.org/10.1007/978-1-4939-7808-3_23
  • Farajollahi, F., Seidenstücker, A., Altintoprak, K., Walther, P., Ziemann, P., Plettl, A., Marti, O., Wege, C., Gliemann, H. (2018). Electrochemically-driven insertion of biological nanodiscs into solid state membrane pores as a basis for “pore-in-pore” membranes. Nanomaterials, 8, 237. https://doi.org/10.3390/nano8040237
  • Lomonossoff, G.P., Wege, C. (2018). Chapter Six - TMV Particles: The Journey From Fundamental Studies to Bionanotechnology Applications, in: Palukaitis, P., Roossinck, M.J. (Eds.), Advances in Virus Research, 102, Academic Press, pp. 149-176. https://doi.org/10.1016/bs.aivir.2018.06.003
  • Icik, E., Eiben, S., Schädel, N., Kupka, J., Martini, M., Wege, C., Laschat, S. (2018). Plant virus hybrid materials based on tobacco mosaic virus and small organic cross-linkers. Bioinspired, Biomimetic and Nanobiomaterials, 7, 187-193. https://doi.org/10.1680/jbibn.18.00016
  • Krapp, S., Schuy, C., Greiner, E., Stephan, I., Alberter, B., Funk, C., Marschall, M., Wege, C., Bailer, S., Kleinow, T., Krenz, B. (2017). Begomoviral movement protein effects in human and plant cells: towards new potential interaction partners. Viruses, 9, 334.
     
  • Altintoprak, K., Seidenstücker, A., Krolla-Sidenstein, P., Plettl, A., Jeske, H., Gliemann, H., Wege, C. (2017). RNA-stabilized protein nanorings: high-precision adapters for biohybrid design. Bioinspired, Biomimetic Nanobiomater., 6, 208-223.
     
  • Schenk, A., Eiben, S., Goll, M., Reith, L., Kulak, A.N., Meldrum, F., Jeske, H., Wege, C., Ludwigs, S., 2017. Virus-directed formation of electrocatalytically active nanoparticle-based Co 3O 4 tubes. Nanoscale, 9, 6334-6345, doi:10.1039/C7NR00508C
     
  • Lemloh, M.-L., Altintoprak, K., Wege, C., Weiss, I., Rothenstein, D. (2017). Biogenic and synthetic peptides with oppositely charged amino acids as binding sites for mineralization. Materials, 10, 119, doi:10.3390/ma10020119
     
  • Baecker, M., Koch, C., Eiben, S., Geiger, F., Eber, F.J., Gliemann, H., Poghossian, A., Wege, C., Schoening, M.J. (2017). Tobacco mosaic virus as enzyme nanocarrier for electrochemical biosensors. Sens. Actuators, B, 238, 716–722, doi: 10.1016/j.snb.2016.07.096.
     
  • Schneider, A., Eber, F. J., Wenz, N., Altintoprak, K., Jeske, H., Eiben, S. & Wege, C. (2016). Dynamic DNA-controlled "stop-and-go" assembly of well-defined protein domains on RNA-scaffolded TMV-like nanotubes. Nanoscale, 8, 19853-19866, doi: 10.1039/C6NR03897B
     
  • Shah, S., A. Khan, A. Espinosa, M. Garcia, W. Nuansing, M. Ungureanu, J. Heddle, A. Chuvilin, C. Wege, A. M. Bittner (2016). Virus-templated near-amorphous iron oxide nanotubes. Langmuir, 32, 5899-5908.
     
  • Steinle, T., Kumar, V., Floess, M., Steinmann, A., Marangoni, M., Koch, C., Wege, C., Cerullo, G., Giessen, H. (2016). Synchronization-free all-solid-state laser system for stimulated Raman scattering microscopy. Light: Sci. Appl., 5, e16149, doi: 10.1038/lsa.2016.149.
     
  • Koch, C., Eber, F.J., Azucena, C., Förste, A., Walheim, S., Schimmel, T., Bittner, A., Jeske, H., Gliemann, H., Eiben, S., Geiger, F., Wege, C. (2016). Novel roles for well-known players: from tobacco mosaic virus pests to enzymatically active assemblies. Beilstein J. Nanotechnol., 7, 613-629.
     
  • Koch, C., Wabbel, K., Eber, F.J., Krolla-Sidenstein, P., Azucena, C., Gliemann, H., Eiben, S., Geiger, F. & Wege, C. (2015). Modified TMV particles as beneficial scaffolds to present sensor enzymes. Frontiers in Plant Science, 6, 1137, DOI: 10.3389/fpls.2015.01137
     
  • Weigel, K., Pohl, J.O., Wege, C., Jeske, H. (2015). A population genetic perspective on geminivirus infection. J. Virol.,  89, 11926-11934.
     
  • Altintoprak, K., Seidenstücker, A., Welle, A., Eiben, S., Atanasova, P., Stitz, N., Plettl, A., Bill, J., Gliemann, H., Jeske, H., Rothenstein, D., Geiger, F. & Wege, C. (2015). Peptide-equipped tobacco mosaic virus templates for selective and controllable biomineral deposition. Beilstein J. Nanotechnol., 6, 1399–1412.
     
  • Krenz, B., Deuschle, K., Deigner, T., Unseld, S., Kepp, G., Wege, C., Kleinow, T., Jeske, H. (2015). Early functions of the Abutilon mosaic virus AC2 gene as a replication brake. J. Virol., 89, 3683-3699.
     
  • Shukla, S., Eber, F. J., Nagarajan, A. S., DiFranco, N. A., Schmidt, N. , Wen, A. M., Eiben, S., Twyman, R. M., Wege, C., Steinmetz, N. (2015). The impact of aspect ratio on biodistribution and tumor homing of rigid soft-matter nanorods. Adv. Healthcare Mater., 4, 874-882.
     
  • Eber, F. J., Eiben, S., Jeske, H., Wege, C. (2015). RNA-controlled assembly of tobacco mosaic virus-derived complex structures: from nanoboomerangs to tetrapods. Nanoscale, 7, 344-355.
     
  • Cremer, C., Kaufmann, R., Gunkel, M., Polanski, F., Müller, P., Degenhard, S., Wege, C., Hausmann, M., Birk, U. J. (2014). Application perspectives of localization microscopy in virology. Histochem. Cell Biol., 142, 43–59.
     
  • Eiben, S., Stitz, N., Eber, F., Wagner, J., Atanasova, P., Bill, J., Wege, C., Jeske, H. (2013). Tailoring the surface properties of tobacco mosaic virions by the integration of bacterially expressed mutant coat protein. Virus Res., 180, 92-96.
     
  • Harder, A., Dieding, M., Walhorn, V., Degenhard, S., Brodehl, A., Wege, C., Milting, H. & Anselmetti, D. (2013). Apertureless scanning near-field optical microscopy of sparsely labelled tobacco mosaic viruses and intermediate filament desmin. Beilstein J. Nanotechnol., 4, 510-516.
     
  • Eber, F. J., Eiben, S., Jeske, H. & Wege, C. (2013). Bottom-up-assembled nanostar colloids of gold cores and tubes derived from tobacco mosaic virus. Angew. Chem. Int. Ed. 52, 7203–7207.
     
  • Geiger, F. C., Eber, F. J., Eiben, S., Mueller, A., Jeske, H., Spatz, J. P., Wege, C. (2013). TMV nanorods with programmed longitudinal domains of differently addressable coat proteins. Nanoscale, 5, 3808-3816
     
  • Kadri, A., Wege, C., Jeske, H. (2013). In vivo self-assembly of TMV-like particles in yeast and bacteria for nanotechnological applications. J. Virol. Methods, 189, 328-340.
     
  • Bittner, A. M., Alonso, J. M., Górzny, M. L., Wege, C. (2013). Nanoscale science and technology with plant viruses and bacteriophages. In: Structure and physics of viruses: an integrated textbook, pp. 667-702. Edited by M.G. Mateu. Dordrecht: Springer Science+Business Media. ISBN 978-94-007-6551-1. Series: Subcellular Biochemistry (Harris, J.R., Series Ed.), ISSN: 0306-0225.
     
  • Khan, A., Fox, E., Górzny, M., Nikulina, E., Brougham, D., Wege, C., Bittner, A.M. (2013). pH control of the electrostatic binding of gold and iron oxide nanoparticles to tobacco mosaic virus. Langmuir, 29, 2094-2098.
     
  • Richert, C., Said, H., Schuller, V., Eber, F., Wege, C. & Liedl, T. (2013). M1.3 - A Small Scaffold for DNA Origami. Nanoscale, 5, 284-290.
     
  • Wege, C., Eber, F.J., Azucena, C., Degenhard, S., Geiger, F., Bittner, A. M., Walheim, S., Förste, A., Huang, C., Schimmel, T., Jeske, H., Gliemannn, H. (2013). “Functionality-on-a-stick”: complex self-assembling virus derivatives – fabrication, activation and integration into technical environments. In "Advances in Nanotechnology - Physics, Chemistry, and Biology of Functional Nanostructures" (T. Schimmel, H. v. Löhneysen, and M. Barcewski, Eds.), ISBN 978-3-00-039257-3; pp. 97-125. Schriftenreihe der Baden-Württemberg-Stiftung gGmbH, Karlsruhe, ISSN 1610-4269.
     
  • Azucena, C., Eber, F. J., Trouillet, V., Hirtz, M., Heissler, S., Franzreb, M., Fuchs, H., Wege, C. & Gliemann, H. (2012). New approaches for bottom-up assembly of tobacco mosaic virus-derived nucleoprotein tubes on defined patterns on silica- and polymer-based substrates. Langmuir; 28, 14867-14877.
     
  • Wyant, P. S., Kober ,S., Schwierzok, A., Kocher, C., Schäfer, B., Jeske, H. and Wege, C. (2012). Cloned Tomato golden mosaic virus back in tomatoes. Virus Res., 167, 397-403.
     
  • Balci, S., Hahn, K., Kopold, P., Kadri, A., Wege, C., Kern, K. and A.M. Bittner. (2012). Electroless synthesis of 3 nm wide alloy nanowires inside Tobacco mosaic virus. Nanotechnology, 23, 045603 (7pp).
     
  • Atanasova, P., Rothenstein, D., Schneider, J. J., Hoffmann, R. C., Dilfer, S., Eiben, S., Wege, C., Jeske, H. & Bill, J. (2011). Virus-templated synthesis of ZnO nanostructures and formation of field-effect transistors. Adv. Mat. , 23, 4918-4922.
     
  • Cremer, C., Kaufmann, R., Gunkel, M., Pres, S., Weiland, Y., Mueller, P., Ruckelshausen, T., Lemmer, P., Geiger, F., Degenhard, S., Wege, C., Lemmermann, N. A. W., Holtappels, R., Strickfaden, H. & Hausmann, M. (2011). Superresolution imaging of biological nanostructures by Spectral Precision Distance Microscopy (SPDM). Biotechnol. J., 6, 1037-1051.
     
  • Sardo, L., Wege, C., Kober, S., Kocher, C., Accotto, G. P. & Noris, E. (2011). RNA viruses and their silencing suppressors boost Abutilon mosaic virus, but not the Old World Tomato yellow leaf curl Sardinia virus. Virus Res., 161. 170-180
     
  • Mueller, A., Eber, F. J., Azucena, C., Petershans, A., Bittner, A. M., Gliemann, H., Jeske, H., and Wege, C. (2011). Inducible site-selective bottom-up assembly of virus-derived nanotube arrays on RNA-equipped wafers. ACS Nano, 5, 4512-4520
     
  • Kadri, A., Maiss, E., Amsharov, N., Bittner, A., Balci, S., Kern, K., Jeske, H., and Wege, C. (2011). Engineered tobacco mosaic virus mutants with distinct physical characteristics in planta and enhanced metallization properties. Virus Res. 157, 35-46.
     
  • Wege, C., Jeske, H., Mueller, A., Eber, F.J., Kadri, A., Balci, S., Baralia, G., Amsharov, N., Petershans, A., Azucena, C., Gliemann, H., Thonke, K., Schirra, M., Wu, Z., Krill III, C., Bittner, A.M. (2011). Plant viral nanoscale biotemplates: From virowires to dumbbells and arrays. In "Nanotechnology - Fundamentals and Applications of Functional Nanostructures" (T. Schimmel, H. v. Löhneysen, and M. Barcewski, Eds.), ISBN 978-3-00-030810-9; pp. 385-409. Baden-Württemberg-Stiftung, Karlsruhe.
     
  • Krenz, B., Windeisen, V., Wege, C., Jeske, H., and Kleinow, T. (2010). A plastid-targeted heat shock cognate 70 kDa protein interacts with the Abutilon mosaic virus movement protein. Virology, 401, 6-17.
     
  • Krenz, B., Wege, C., and Jeske, H. (2010). Cell-free construction of disarmed Abutilon mosaic virus-based gene silencing vectors. J. Virol. Methods, 169, 129-137.
     
  • Mueller, A., Kadri, A., Jeske, H., and Wege, C. (2010). In vitro assembly of Tobacco mosaic virus coat protein variants derived from fission yeast expression clones or plants. J. Virol. Methods, 166, 77–85.
     
  • Wu, Z., Mueller, A., Degenhard, S., Ruff, S. E., Geiger, F., Bittner, A., Wege, C. & Krill III, C. (2010). Enhancing the magnetoviscosity of ferrofluids by the addition of biological nanotubes. ACS Nano, 4, 4531-4538.
     
  • Wu, Z., Zierold, R., Mueller, A., Ruff, S. E., Ma, C., Khan, A. A., Geiger, F., Sommer, B. A., Knez, M., Nielsch, K., Bittner, A. M., Wege, C. & Krill III, C. (2010). Preparation and magnetoviscosity of nanotube ferrofluids by viral scaffolding and ALD on porous templates. Phys. Stat. Sol. B,  247, 2412-2423.
     
  • Balci, S., Bittner, A. M., Schirra, M., Thonke, K., Sauer, R., Hahn, K., Kadri, A., Wege, C., Jeske, H., and Kern, K. (2009). Catalytic coating of virus particles with zinc oxide. Electrochimica Acta, 54, 5149-5154.
     
  • Kleinow, T., Tanwir, F., Kocher, C., Krenz, B., Wege, C., and Jeske, H. (2009). Expression dynamics and ultrastructural localization of epitope-tagged Abutilon mosaic virus nuclear shuttle and movement proteins in Nicotiana benthamiana cells. Virology, 391, 212-220.
      
  • Wege, C. (2009). Mixed infections of geminiviruses and unrelated RNA viruses or viroids in tomato: a multitude of effects with a highly probable impact on epidemiology and agriculture. In Crop Plant Resistance to Biotic and Abiotic Factors: Current Potential and Future Demands, pp. 233-241. Edited by F. Feldmann, D. V. Alford & C. Furk. Braunschweig, Germany: Deutsche Phytomedizinische Gesellschaft.
     
  • Balci, S., Leinberger, D. M., Knez, M., Bittner, A., Boes, F., Kadri, A., Wege, C., Jeske, H., and Kern, K. (2008). Printing and aligning mesoscale patterns of Tobacco mosaic viruses on surfaces. Adv. Mater. 20, 2195-2200.
     
  • Jeske, H., Wege, C., Kern, K., and Bittner, A. (2008). Plant viral nanoscale biotemplates: on the road to virowires. In "Nanotechnology - Physics, Chemistry, and Biology of Functional Nanostructures" (T. Schimmel, H. v. Löhneysen, M. Barcewski, and C. Obermair, Eds.), Vol. 32, pp. 421-454. Landesstiftung Baden-Württemberg gGmbH, Karlsruhe.
     
  • Kleinow, T., Holeiter, G., M., Nischang, Stein, M., Karayavuz, M., Wege, C., and Jeske, H. (2008). Post-translational modifications of Abutilon mosaic virus movement protein (BC1) in fission yeast. Virus Res. 131, 86-94.
     
  • Balci, S., Noda, K., Bittner, A. M., Kadri, A., Wege, C., Jeske, H., and Kern, K. (2007). Self-assembly of metal-virus nanodumbbells. Angew. Chem. Int. Ed. 46(17), 3149-3151.
     
  • Balci, S., Noda, K., Bittner, A. M., Kadri, A., Wege, C., Jeske, H., and Kern, K. (2007). Selbstorganisation von Metall-Virus-Nanohanteln. Angew. Chem. 119(17), 3210-3212.
     
  • Frischmuth, S., Wege, C., Hülser, D., and Jeske, H. (2007). The movement protein BC1 promotes redirection of the nuclear shuttle protein BV1 of Abutilon mosaic geminivirus to the plasma membrane in fission yeast. Protoplasma, 230, 117-123.
     
  • Pohl, D., and Wege, C. (2007). Synergistic pathogenicity of a phloem-limited begomovirus and tobamoviruses despite negative interference. J. Gen. Virol. 88, 1034-1040.
     
  • Wege, C. (2007). Movement and localization of Tomato yellow leaf curl viruses in the infected plant. In "Tomato yellow leaf curl virus disease" (H. Czosnek, Ed.), pp. 185-206. Springer, Dordrecht.
     
  • Wege, C., and Pohl, D. (2007). Abutilon mosaic virus DNA B component supports mechanical virus transmission, but does not counteract begomoviral phloem limitation in transgenic plants. Virology, 365, 173-186.
     
  • Wege, C. & D. Siegmund (2007). Synergism of a DNA and an RNA virus: Enhanced tissue infiltration of the begomovirus Abutilon mosaic virus (AbMV) mediated by Cucumber mosaic virus (CMV). Virology, 357, 10-28.
     
  • Balci, S., Bittner, A. M., Hahn, K., Scheu, C., Knez, M., Kadri, A., Wege, W., Jeske, H., and Kern, K. (2006). Copper nanowires within the central channel of Tobacco mosaic virus particles. Electrochim. Acta, 51, 6251-6257.
     
  • Knez, M., Kadri, A., Wege, C., Gösele, U., Jeske, H., and Nielsch, K. (2006). Atomic layer deposition on biological macromolecules: Metal oxide coating of Tobacco mosaic virus and ferritin. Nano Letters, 6, 1172-1177.
     
  • aus dem Siepen, M., Pohl, J., Koo, B.-J., Wege, C., and Jeske, H. (2005). Poinsettia latent virus is not a cryptic virus, but a natural polerovirus-sobemovirus hybrid. Virology, 336, 240-250.
     
  • Frischmuth, S., Kleinow, T., Aberle, H.-J., Wege, C., Hülser, D., and Jeske, H. (2004). Yeast two-hybrid systems confirm the membrane-association and oligomerization of BC1 but do not detect an interaction of the movement proteins BC1 and BV1 of Abutilon mosaic geminivirus. Arch. Virol., 149, 2349-2364.
     
  • Hehnle, S., Wege, C., and Jeske, H. (2004). The interaction of DNA with the movement proteins of geminiviruses revisited. J. Virol. 78, 7698-7706.
     
  • Knez, M., Sumser, M., Bittner, A., Wege, C., and Jeske, H. (2004). Spatially selective nucleation of metal clusters on the tobacco mosaic virus. Adv. Funct. Mater. 14, 116-124.
     
  • Knez, M., Sumser, M., Bittner, A., Wege, C., Jeske, H., Hoffmann, D. M. P., Kuhnke, K., and Kern, K. (2004). Binding the Tobacco mosaic virus to inorganic surfaces. Langmuir, 20, 411-447.
     
  • Morilla, G., Krenz, B., Jeske, H., Bejarano, E. R., and Wege, C. (2004). Tête à tête of Tomato yellow leaf curl virus (TYLCV) and Tomato yellow leaf curl Sardinia virus (TYLCSV) in single nuclei. J. Virol. 78, 10715–10723.
     
  • Knez, M., Bittner, A., Boes, F., Wege, C., Jeske, H., Maiss, E., and Kern, K. (2003). Biotemplate synthesis of 3 nm nickel and cobalt nanowires. Nano Letters, 3, 1079-1082.
     
  • Aberle, H.-J., Rütz, M.-L., Karayavuz, M., Frischmuth, S., Wege, C., Hülser, D., and H. Jeske (2002): Localizing BC1 movement proteins of Abutilon mosaic geminivirus in yeasts by subcellular fractionation and freeze-fracture immuno-labelling. Arch. Virol. 147, 103-107.
     
  • Knez, M., Sumser, M., Bittner, A., Wege, C., Jeske, H., Kooi, S., Burghard, M., and Kern, K. (2002). Electrochemical modification of individual nano-objects. J. Electroanalyt. Chem. 522, 70-74.
     
  • Saunders, K., C. Wege, K. Veluthambi, H. Jeske, and J. Stanley (2001): The distinct disease phenotypes of the common and yellow vein strains of Tomato golden mosaic virus are determined by nucleotide differences in the 3'-terminal region of the gene encoding the movement protein. J. Gen. Virol. 82, 45-51.
     
  • Wege, C., K. Saunders, J. Stanley, and H. Jeske (2001): Comparative analysis of tissue tropism of bipartite geminiviruses. J. Phytopathology, 149, 359-368.
     
  • Zhang, S.C., Wege, C., and H. Jeske (2001): Movement proteins (BC1 and BV1) of Abutilon mosaic geminivirus are cotransported in and between cells of sink but not of source leaves as detected by Green Fluorescent Protein tagging. Virology, 290: 249-260.
     
  • Wege, C., R.-D. Gotthardt, T. Frischmuth, and H. Jeske (2000): Fulfilling Koch's postulates for Abutilon mosaic virus. Arch. Virol. 145, 2217-2225.
     
  • Wege, C. and H. Jeske (1998): Abutilon mosaic geminivirus proteins expressed and phosphorylated in Escherichia coli. J. Phytopathology, 146, 613-621.
 

since
2019

Head of Research Unit
Molecular and Synthetic Plant Virology (IBBS)

Oct 2011

 

Professor (extraordinary professor; Apl. Prof. [außerplanmäßiger Prof.] / Professorate Faculty Member), University of Stuttgart, Faculty 4: Energy-, Process- and Bio-Engineering

since 2010

Academic Director,
Institute of Biomaterials and Biomoleculary Systems (IBBS), University of Stuttgart

since 2007

 

Privatdozentin (Priv.-Doz.),
University of Stuttgart

June 2007

Habilitation degree in "Molecular Biology and Plant Virology",
Faculty of Geo- and Biosciences, University of Stuttgart

since 2003

Principal Investigator / Responsible Project Leader

1998 – 2000

Research Associate (Wissenschaftliche Assistentin C1)

March 1998

Doctoral Degree (Dr. rer. nat.), Univ. of Stuttgart

1994 - 1998

Scientific Staff Member (Wissenschaftliche Mitarbeiterin),
Dpt. of Molecular Biology and Plant Virology, University of Stuttgart

1992 -
1994

Research in Norwich/England (John Innes Centre) and Hamburg/Germany (Institute of General Botany); co-organizator lab set-up in Stuttgart

1992

Graduation: a) Biology (Dipl.-Biol.) and b) Journalism, University of Hamburg

1986 - 1988

Traineeship and casual work for public radio NDR / Editorial Office for Science & Environment, Hamburg

1985 - 1991

Studies of a) Biology (Diplom) and b) Journalism (in parallel), University of Hamburg
since
2022		 Head of Examination Board B.Sc./M.Sc. Technical Biology

since 2014

Coordinator of Research Focus "NanoBioMater" at the University of Stuttgart ("Nanobiomaterials Project House" funded by the Carl-Zeiss-Stiftung) in collaboration with the Institute of Interfacial Process Engineering and Plasma Technology (IGVP) and the Institute of Organic Chemistry (IOC)

2013
-2021

Member of the Scientific Advisory Board of the Leibniz Institute – DSMZ German Collection of Microorganisms and Cell Cultures GmbH (Deutsche Sammlung für Mikroorganismen und Zellkulturen), Braunschweig

since 2012

Coordinator Research Area "Biofunctional Nanostructures & Surfaces" of the Research Network "Functional Nanostructures", Baden-Württemberg Stiftung gGmbH

since 2011

Faculty of Energy-, Process- and Bio-Engineering: professorate faculty member

since 2011

Member of the Joint Committee "Food Chemistry" of the Universities of Stuttgart and Hohenheim

since 2004

International Reviewer (project funding, publications, Ph.D. theses, institutional and study organization)

since 2004

Review Board Member Hans-Boeckler-Stiftung, study and Ph.D. grants

2003
-2015

Examiner "1st Staatsexamen Biologie" (part of qualification programme "Food Chemistry" [Staatsexamen], Universities Stuttgart and Hohenheim)

since
2003

Safety Officer, Institute of Biology, Univ. Stuttgart

since 1996

Responsibilities in Academic Self-Administration

(2000-2004 Academic Senate of the University of Stuttgart: scientific staff delegate; 1996-2010 Faculty Council Fac. 4: scientific staff delegate (up to 2000: deputy; up to 2007 Faculty of Geo- and Biosciences, then Energy-, Process- and Bio-Engineering);

Member of Senate committees and reviewer boards (since 2016 deputy member of the Commission for Good Scientific Practice; 2006-09 scientific staff delegate of the Fact-Finding Commission on Scientific Misconduct; 2002-12 Senate Committee Research and Technology; 2000-02 Senate Committee Education; 2000-10 Senate committees and reviewer boards "International Studies" (since 2006 substitute) and "Students' Grants & Scholarships");

2008-10 Faculty's Equal Opportunity Commissioner - substitute)
 
 
since
2019

Journal Club "Molecular Biology" (Seminar M.Sc.; Wege & Kleinow)

since
2019

Seminar "Bioethics" (B.Sc. and Fundamental Qualifications; Wege & Fritz, previously H. Jeske)

since
2019

M.Sc. Teaching Module (Lecture, Laboratory Course and Seminar for Graduates) "Bionanotechnology, Smart Materials and Molecular Biology of Plant Viruses" (Wege & Kleinow)

2013 - 2018

M.Sc. Teaching Module (Lecture, Laboratory Course and Seminar for Graduates) "Nanobiotechnology and Hybrid Materials with Plant Virus Derivatives" (Wege et al.)

2013 - 2018

M.Sc. Teaching Module (Lecture, Laboratory Course and Seminar for Graduates) "Molecular Plant Virology" (Wege, Jeske et al.)

since
2011

 

"Molecular Biology"
(Theory and Exercise Course for Undergraduates / B.Sc., Module Techn. Biol. III, Jeske, Wege, Kleinow et al.)

2010 - 2012

"Plant Virology & Nanobiotechnology"
(Laboratory Course and Seminar for Graduates / M.Sc.)

since 2009

"Plant Cells, Tissues, and Organs: Structures, Functions & Technologically Relevant Applications" (Lectures and Laboratory Exercises within cooperative module "Basics in Technical Biology" for Undergraduates / B.Sc.; Module Techn. Biol. I (up to 2019) and Food Chemistry)

since 2007

Scientific Examiner (B.Sc./M.Sc./Dr. rer. nat. [Ph.D.], exams and theses)

since 2002

Internships for Technician Trainees
(Biotechnological Technician Training, collaboration with Staatschule Stuttgart-Hohenheim)

2001 - 2009

"Plant Virology" 
(German Diplom Teaching Module: Laboratory Course and Seminar for Graduates; Jeske & Wege)

since 1995

Supervision of Scientific Laboratory Projects and Theses

1993 - 2001

"Molecular Biology"  
(German Diplom Teaching Module: Laboratory Course and Seminar for Graduates; Bernhardt oder Frischmuth & Wege)

since 1993

Seminar "Journal Club: Molecular Biology and Plant Virology"
(Seminar for Graduates / M.Sc/.; Jeske, Wege, Kleinow and team)

since 1992

Seminars and practical training "Scientific Writing and Presentation"
(Graduates / M.Sc., and PhD / Dr. rer. nat. candidates; occasionally, in- and external activities)
 
  • BioNano Collaborative Workshop at the University of Aachen
    Joint Event at the Institute of Nano- und Biotechnologies (INB, 2015)  >>mehr
     
  • Christina Wege - von Pflanzenviren zu Biomaterialien
    Forscherporträt durch die BIOPRO Baden-Württemberg GmbH (2014)  >>mehr
     
  • Ein neuer Akzent in der Forschungslandschaft
    Eröffnung des Projekthauses NanoBioMater (2014, idw-online.de) >> mehr
     
  • Ein Virus im Transistor
    FERCHAU Engineering News (2012)  >>mehr
     
  • Viren als Vorlage für Nanostrukturen
    VBIO News (2007)  >>mehr
     
  • Pflanzenviren bauen Transistoren
    Neues Deutschland (2007)  >>mehr
     
  • Golden Nano-Dumbbells
    phys.org (2007)  >>mehr
To the top of the page