This image shows Arnd G. Heyer

Arnd G. Heyer

Prof. Dr.

Head of Department
IBBS
Dept. Plant Biotechnology

Contact

+49 711 685 65050
 +49 711 685 65096

Pfaffenwaldring 57
70569 Stuttgart
Deutschland
Room: 9.348

Publications:
  1. Friedrichs, N., Shokouhi, D., Heyer, A.G.: Flux Calculation for Primary Metabolism Reveals Changes in Allocation of Nitrogen to Different Amino Acid Families When Photorespiratory Activity Changes. International Journal of Molecular Sciences. 25, (2024). https://doi.org/10.3390/ijms25158394.
  2. Kraemer, K., Kepp, G., Brock, J., Stutz, S., Heyer, A.G.: Acclimation to elevated CO2 affects the C/N balance by reducing de novo N-assimilation. Physiologia Plantarum. 174, e13615 (2022). https://doi.org/10.1111/ppl.13615.
  3. Hoermiller, I.I., Funck, D., Schönewolf, L., May, H., Heyer, A.G.: Cytosolic proline is required for basal freezing tolerance in Arabidopsis. Plant, Cell & Environment. (2022). https://doi.org/10.1111/pce.14196.
  4. Kraemer, K., Brock, J., Heyer, A.G.: Interaction of Nitrate Assimilation and Photorespiration at Elevated CO2. Frontiers in Plant Science. 13, (2022). https://doi.org/10.3389/fpls.2022.897924.
  5. Roth-Nebelsick, A., Thiv, M., Malkowsky, Y., Schott, R., Heyer, A.: Structure and functional anatomy of the gas exchange apparatus of leafless orchids: evidence for a control mechanism? Botanical Journal of the Linnean Society. (2021). https://doi.org/10.1093/botlinnean/boab021.
  6. Helisch, H., Keppler, J., Detrell, G., Belz, S., Ewald, R., Fasoulas, S., Heyer, A.G.: High density long-term cultivation of Chlorella vulgaris SAG 211-12 in a novel microgravity-capable membrane raceway photobioreactor for future bioregenerative life support in SPACE. Life Sciences in Space Research. 24, 91–107 (2020). https://doi.org/10.1016/j.lssr.2019.08.001.
  7. Krämer, K., Krämer, J., Heyer, A.: paropt: Parameter Optimizing of ODE-Systems. University of Stuttgart, University of Stuttgart, Institute of Biomaterials and Biomolecular Systems (2020).
  8. Hell, A.F., Kretzschmar, F.S., Simões, K., Heyer, A.G., Barbedo, C.J., Braga, M.R., Centeno, D.C.: Metabolic Changes on the Acquisition of Desiccation Tolerance in Seeds of the Brazilian Native Tree Erythrina speciosa. Frontiers in Plant Science. 10, 1356 (2019). https://doi.org/10.3389/fpls.2019.01356.
  9. Küstner, L., Fürtauer, L., Weckwerth, W., Nägele, T., Heyer, A.G.: Subcellular dynamics of proteins and metabolites under abiotic stress reveal deferred response of the Arabidopsis thaliana hexokinase‐1 mutant gin2‐1 to high light. Plant Journal. 100, 456–472 (2019). https://doi.org/10.1111/tpj.14491.
  10. Fürtauer, L., Küstner, L., Weckwerth, W., Heyer, A.G., Nägele, T.: Resolving subcellular plant metabolism. Plant Journal. 100, 438–455 (2019). https://doi.org/10.1111/tpj.14472.
  11. Küstner, L., Nägele, T., Heyer, A.G.: Mathematical modeling of diurnal patterns of carbon allocation to shoot and root in Arabidopsis thaliana. npj Systems Biology and Applications. 5, 4-- (2019). https://doi.org/10.1038/s41540-018-0080-1.
  12. Mishra, K.B., Mishra, A., Kubásek, J., Urban, O., Heyer, A.G., Govindjee: Low temperature induced modulation of photosynthetic induction in non-acclimated and cold-acclimated Arabidopsis thaliana: chlorophyll a fluorescence and gas-exchange measurements. Photosynthesis Research. (2018). https://doi.org/10.1007/s11120-018-0588-7.
  13. Birami, B., Gattmann, M., Heyer, A.G., Grote, R., Arneth, A., Ruehr, N.: Heat waves alter carbon allocation and increase mortality of Aleppo pine under dry conditions. Frontiers in Forests and Global Change. 1, 8 (2018). https://doi.org/doi: 10.3389/ffgc.2018.00008.
  14. Hoermiller, I.I., Ruschhaupt, M., Heyer, A.G.: Mechanisms of frost resistance in Arabidopsis thaliana. Planta. 248, 827–835 (2018). https://doi.org/10.1007/s00425-018-2939-1.
  15. Brauner, K., Birami, B., Brauner, H.A., Heyer, A.G.: Diurnal periodicity of assimilate transport shapes resource allocation and whole-plant carbon balance. The Plant Journal. 94, 776–789 (2018). https://doi.org/10.1111/tpj.13898.
  16. Hoermiller, I.I., Naegele, T., Augustin, H., Stutz, S., Weckwerth, W., Heyer, A.G.: Subcellular reprogramming of metabolism during cold acclimation in Arabidopsis thaliana. Plant Cell Environ. 40, 602–610 (2017). https://doi.org/10.1111/pce.12836.
  17. Nissen, M., Shcherbakov, D., Heyer, A., Brümmer, F., Schill, R.O.: Behaviour of the plathelminth Symsagittifera roscoffensis under different light conditions and the consequences for the symbiotic algae Tetraselmis convolutae. Journal of Experimental Biology. 218, 1693--1698 (2015). https://doi.org/10.1242/jeb.110429.
  18. Brauner, K., Stutz, S., Paul, M., Heyer, A.G.: Measuring whole plant CO2 exchange with the environment reveals opposing effects of the gin2–1 mutation in shoots and roots of Arabidopsis thaliana. Plant Signaling Behav. 10, e973822 (2015). https://doi.org/10.4161/15592324.2014.973822.
  19. Xu, E., Vaathera, L., Hörak, H., Hincha, D.K., Heyer, A.G., Brosche, M.: Quantitative trait loci mapping and transcriptome analysis reveal candidate genes regulating the response to ozone in Arabidopsis thaliana. Plant, Cell & Environment. 38, 1418–1433 (2015). https://doi.org/10.1111/pce.12499.
  20. Mishra, A., Heyer, A., Mishra, K.: Chlorophyll fluorescence emission can screen cold tolerance of cold acclimated Arabidopsis thaliana accessions. Plant Methods. 10, 38 (2014). https://doi.org/10.1186/1746-4811-10-38.
  21. Do, P.T., Drechsel, O., Heyer, A.G., Hincha, D.K., Zuther, E.: Changes in free polyamine levels, expression of polyamine biosynthesis genes, and performance of rice cultivars under salt stress: a comparison with responses to drought. Frontiers in Plant Science. 5, (2014). https://doi.org/10.3389/fpls.2014.00182.
  22. Brauner, K., Hörmiller, I., Nägele, T., Heyer, A.G.: Exaggerated root respiration accounts for growth retardation in a starchless mutant of Arabidopsis thaliana. Plant J. 79, 82--91 (2014). https://doi.org/10.1111/tpj.12555.
  23. Meissner, M., Orsini, E., Ruschhaupt, M., Melchinger, A.E., Hincha, D.K., Heyer, A.G.: Mapping quantitative trait loci for freezing tolerance in a recombinant inbred line population of Arabidopsis thaliana accessions Tenela and C24 reveals REVEILLE1 as negative regulator of cold acclimation. Plant Cell Environ. 36, 1256–1267 (2013). https://doi.org/10.1111/pce.12054.
  24. Do, P.T., Degenkolbe, T., Erban, A., Heyer, A.G., Kopka, J., Köhl, K.I., Hincha, D.K., Zuther, E.: Dissecting Rice Polyamine Metabolism under Controlled Long-Term Drought Stress. PLOS ONE. 8, 1–14 (2013). https://doi.org/10.1371/journal.pone.0060325.
  25. Distelbarth, H., Nägele, T., Heyer, A.: Responses of antioxidant enzymes to cold and highlight are not correlated to freezing tolerance in natural accessions of Arabidopsis thaliana. Plant Biol. 15, 982--990 (2013). https://doi.org/10.1111/j.1438-8677.2012.00718.x.
  26. Nägele, T., Heyer, A.G.: Approximating subcellular organisation of carbohydrate metabolism during cold acclimation in different natural accessions of Arabidopsis thaliana. New Phytol. 198, 777--787 (2013). https://doi.org/10.1111/nph.12201.
  27. Nägele, T., Stutz, S., Hörmiller, I.I., Heyer, A.G.: Identification of a metabolic bottleneck for cold acclimation in Arabidopsis thaliana. Plant J. 72, 102–114 (2012). https://doi.org/10.1111/j.1365-313X.2012.05064.x.
  28. Hengherr, S., Heyer, A.G., Brümmer, F., Schill, R.O.: Trehalose and Vitreous States: Desiccation Tolerance of Dormant Stages of the Crustaceans Triops and Daphnia. Physiological and Biochemical Zoology: Ecological and Evolutionary Approaches. 84, 147--153 (2011). https://doi.org/10.1086/658499.
  29. Iftime, D., Hannah, M.A., Peterbauer, T., Heyer, A.G.: Stachyose in the cytosol does not influence freezing tolerance of transgenic Arabidopsis expressing stachyose synthase from adzuki bean. Plant Science. 180, 24--30 (2011). https://doi.org/10.1016/j.plantsci.2010.07.012.
  30. Zuther, E., Hoermiller, I.I., Heyer, A.G.: Evidence against sink limitation by the sucrose-to-starch route in potato plants expressing fructosyltransferases. Physiol. Plant. 143, 115--125 (2011). https://doi.org/10.1111/j.1399-3054.2011.01495.x.
  31. Mishra, A., Mishra, K.B., Hoermiller, I.I., Heyer, A.G., Nedbal, L.: Chlorophyll fluorescence emission as a reporter on cold tolerance in Arabidopsis thaliana accessions. Plant Signaling Behav. 6, 301--310 (2011). https://doi.org/10.4161/psb.6.2.15278.
  32. Wingenter, K., Trentmann, O., Winschuh, I., Hörmiller, I.I., Heyer, A.G., Reinders, J., Schulz, A., Geiger, D., Hedrich, R., Neuhaus, H.E.: A member of the mitogen-activated protein 3-kinase family is involved in the regulation of plant vacuolar glucose uptake. Plant J. 68, 890--900 (2011). https://doi.org/10.1111/j.1365-313X.2011.04739.x.
  33. Knaupp, M., Mishra, K.B., Nedbal, L., Heyer, A.G.: Evidence for a role of raffinose in stabilizing photosystem II during freeze--thaw cycles. Planta. 234, 477--486 (2011). https://doi.org/10.1007/s00425-011-1413-0.
  34. Nägele, T., Kandel, B.A., Frana, S., Meissner, M., Heyer, A.G.: A systems biology approach for the analysis of carbohydrate dynamics during acclimation to low temperature in Arabidopsis thaliana. FEBS J. 278, 506--518 (2011). https://doi.org/10.1111/j.1742-4658.2010.07971.x.
  35. Henkel, S., Nägele, T., Hörmiller, I., Sauter, T., Sawodny, O., Ederer, M., Heyer, A.G.: A systems biology approach to analyse leaf carbohydrate metabolism in Arabidopsis thaliana. EURASIP Journal on Bioinformatics and Systems Biology. 2011, 2 (2011). https://doi.org/10.1186/1687-4153-2011-2.
  36. Nägele, T., Henkel, S., Hörmiller, I., Sauter, T., Sawodny, O., Ederer, M., Heyer, A.G.: Mathematical modeling of the central carbohydrate metabolism in Arabidopsis reveals a substantial regulatory influence of vacuolar invertase on whole plant carbon metabolism. Plant Physiol. 153, 260--272 (2010). https://doi.org/10.1104/pp.110.154443.
  37. Wingenter, K., Schulz, A., Wormit, A., Wic, S., Trentmann, O., Hoermiller, I.I., Heyer, A.G., Marten, I., Hedrich, R., Neuhaus, H.E.: Increased Activity of the Vacuolar Monosaccharide Transporter TMT1 Alters Cellular Sugar Partitioning, Sugar Signaling, and Seed Yield in Arabidopsis. Plant Physiol. 154, 665--677 (2010). https://doi.org/10.1104/pp.110.162040.
  38. Livingston, D.P., Hincha, D.K., Heyer, A.G.: Fructan and its relationship to abiotic stress tolerance in plants. Cellular and Molecular Life Sciences. 66, 2007--2023 (2009). https://doi.org/10.1007/s00018-009-0002-x.
  39. Korn, M., Peterek, S., Mock, H.P., Heyer, A.G., Hincha, D.K.: Heterosis in the freezing tolerance, and sugar and flavonoid contents of crosses between Arabidopsis thaliana accessions of widely varying freezing tolerance. Plant Cell Environ. 31, 813--827 (2008). https://doi.org/10.1111/j.1365-3040.2008.01800.x.
  40. Hengherr, S., Heyer, A.G., Kohler, H.R., Schill, R.O.: Trehalose and anhydrobiosis in tardigrades - evidence for divergence in responses to dehydration. FEBS J. 275, 281--288 (2008). https://doi.org/10.1111/j.1742-4658.2007.06198.x.
  41. Hannah, M.A., Kramer, K.M., Geffroy, V., Kopka, J., Blair, M.W., Erban, A., Vallejos, C.E., Heyer, A.G., Sanders, F.E.T., Millner, P.A., Pilbeam, D.J.: Hybrid weakness controlled by the dosage-dependent lethal (DL) gene system in common bean (Phaseolus vulgaris) is caused by a shoot-derived inhibitory signal leading to salicylic acid-associated root death. New Phytol. 176, 537--549 (2007). https://doi.org/10.1111/j.1469-8137.2007.02215.x.
  42. Hincha, D.K., Livingston, D.P., Premakumar, R., Zuther, E., Obel, N., Cacela, C., Heyer, A.G.: Fructans from oat and rye: Composition and effects on membrane stability during drying. Biochimica et Biophysica Acta (BBA) - Biomembranes. 1768, 1611--1619 (2007). https://doi.org/10.1016/j.bbamem.2007.03.011.
  43. Hannah, M.A., Zuther, E., Buchel, K., Heyer, A.G.: Transport and metabolism of raffinose family oligosaccharides in transgenic potato. J. Exp. Bot. 57, 3801--3811 (2006). https://doi.org/10.1093/jxb/erl152.
  44. Hannah, M.A., Wiese, D., Freund, S., Fiehn, O., Heyer, A.G., Hincha, D.K.: Natural genetic variation of freezing tolerance in Arabidopsis. Plant Physiol. 142, 98--112 (2006). https://doi.org/10.1104/pp.106.081141.
  45. Degenkolbe, T., Hannah, M.A., Freund, S., Hincha, D.K., Heyer, A.G., Köhl, K.I.: A quality-controlled microarray method for gene expression profiling. Analytical Biochemistry. 346, 217--224 (2005). https://doi.org/10.1016/j.ab.2005.08.027.
  46. Hannah, M.A., Heyer, A.G., Hincha, D.K.: A Global Survey of Gene Regulation during Cold Acclimation in Arabidopsis thaliana. PLOS Genetics. 1, (2005). https://doi.org/10.1371/journal.pgen.0010026.
  47. Heyer, A.G., Raap, M., Schroeer, B., Marty, B., Willmitzer, L.: Cell wall invertase expression at the apical meristem alters floral, architectural, and reproductive traits in Arabidopsis thaliana. Plant Journal. 39, 161–169 (2004). https://doi.org/10.1111/j.1365-313X.2004.02124.x.
  48. Zuther, E., Büchel, K., Hundertmark, M., Stitt, M., Hincha, D.K., Heyer, A.G.: The role of raffinose in the cold acclimation response of Arabidopsis thaliana. FEBS Lett. 576, 169--173 (2004).
  49. Zuther, E., Kwart, M., Willmitzer, L., Heyer, A.G.: Expression of a yeast-derived invertase in companion cells results in long-distance transport of a trisaccharide in an apoplastic loader and influences sucrose transport. Planta. 218, 759--766 (2004). https://doi.org/10.1007/s00425-003-1148-7.
  50. Rohde, P., Hincha, D.K., Heyer, A.G.: Heterosis in the freezing tolerance of crosses between two Arabidopsis thaliana accessions (Columbia-0 and C24) that show differences in non-acclimated and acclimated freezing tolerance. The Plant Journal. 38, 790–799 (2004). https://doi.org/10.1111/j.1365-313X.2004.02080.x.
  51. Clark, G.T., Zuther, E., Outred, H.A., McManus, M.T., Heyer, A.G.: Tissue-specific changes in remobilisation of fructan in the xerophytic tussock species Festuca novae-zelandiae in response to a water deficit. Functional Plant Biology. 31, 377 (2004). https://doi.org/10.1071/fp03230.
  52. Klotke, J., Kopka, J., Gatzke, N., Heyer, A.G.: Impact of soluble sugar concentrations on the acquisition of freezing tolerance in accessions of Arabidopsis thaliana with contrasting cold adaptation - evidence for a role of raffinose in cold acclimation. Plant Cell Environ. 27, 1395--1404 (2004).
  53. Hincha, D.K., Zuther, E., Heyer, A.G.: The preservation of liposomes by raffinose family oligosaccharides during drying is mediated by effects on fusion and lipid phase transitions. Biochimica et Biophysica Acta (BBA) - Biomembranes. 1612, 172--177 (2003). https://doi.org/10.1016/s0005-2736(03)00116-0.
  54. Hincha, D.K., Zuther, E., Hellwege, E.M., Heyer, A.G.: Specific effects of fructo- and gluco-oligosaccharides in the preservation of liposomes during drying. Glycobiology. 12, 103--110 (2002). https://doi.org/10.1093/glycob/12.2.103.
  55. Popova, A.V., Heyer, A.G., Hincha, D.K.: Differential destabilization of membranes by tryptophan and phenylalanine during freezing: the roles of lipid composition and membrane fusion. Biochimica et Biophysica Acta (BBA) - Biomembranes. 1561, 109--118 (2002). https://doi.org/10.1016/s0005-2736(01)00462-x.
  56. Heyer, A.G., Wendenburg, R.: Gene Cloning and Functional Characterization by Heterologous Expression of the Fructosyltransferase of Aspergillus sydowi IAM 2544. Applied and Environmental Microbiology. 67, 363–370 (2001). https://doi.org/10.1128/AEM.67.1.363-370.2001.
  57. Oliver, A.E., Leprince, O., Wolkers, W.F., Hincha, D.K., Heyer, A.G., Crowe, J.H.: Non-Disaccharide-Based Mechanisms of Protection during Drying. Cryobiology. 43, 151--167 (2001). https://doi.org/10.1006/cryo.2001.2359.
  58. Hellwege, E.M., Czapla, S., Jahnke, A., Willmitzer, L., Heyer, A.G.: Transgenic potato (Solanum tuberosum) tubers synthesize the full spectrum of inulin molecules naturally occurring in globe artichoke (Cynara scolymus) roots. Proceedings of the National Academy of Sciences. 97, 8699–8704 (2000). https://doi.org/10.1073/pnas.150043797.
  59. Hincha, D.K., Hellwege, E.M., Heyer, A.G., Crowe, J.H.: Plant fructans stabilize phosphatidylcholine liposomes during freeze-drying. European Journal of Biochemistry. 267, 535–540 (2000). https://doi.org/10.1046/j.1432-1327.2000.01028.x.
  60. Wolff, D., Czapla, S., Heyer, A.G., Radosta, S., Mischnick, P., Springer, J.: Globular shape of high molar mass inulin revealed by static light scattering and viscometry. Polymer. 41, 8009--8016 (2000). https://doi.org/10.1016/s0032-3861(00)00168-3.
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